Forskning

July 30, 2019

The concentration and prevalence of ochratoxin A in coffee and coffee-based products: a global systematic-review, meta-analysis and meta-regression

A M Khaneghah et al, 2019. The concentration and prevalence of ochratoxin A in coffee and coffee-based products: a global systematic-review, meta-analysis and meta-regression, Fungal Biology, Volume 123 (8).

ABSTRACT

The current investigation was aimed to estimate the prevalence and concentration of ochratoxin A (OTA) in different types of coffee and coffee-based products with the aid of a systematic review and meta-analysis. Therefore, the recommended databases including PubMed, Scopus, and Embase from Jan 1983 to Oct 2018 were screened to retrieve the related citations. In this regard, among 1041 explored articles in the identification step, thirty six articles with 3182 samples were included in the meta-analysis and meta-regression. According to findings, the global pooled concentration and prevalence of OTA was calculated as 3.21 μg/kg (95% CI: 3.08-3.34 μg/kg) and 53.0 % (95% CI: 43.0-62.0), respectively. Also, direct correlations between the increases in poverty as well as the amount of annual precipitation and prevalence of OTA was noted, while with decreasing in HDI the prevalence of OTA in coffee significantly was increased. Moreover, the lowest and highest concentrations of OTA in coffee were observed in Taiwan (0.35 μg/kg) and Turkey (79.0 μg/kg), respectively. The outcome of this meta-analysis can be used for the building of risk assessment models aiming to derive data for the development of specific actions to reduce the exposure to this mycotoxin in coffee and coffee-based products.