Forskning

January 8, 2013

Caffeine intake and its association with urinary incontinence in US men: Results from the National Health and Nutritional Examination Surveys (NHANES) 205-6 and 2007-8

N J Davis et al, 2012, Caffeine intake and its association with urinary incontinence in US men: Results from the National Health and Nutritional Examination Surveys (NHANES) 205-6 and 2007-8, The Journal of Urology, Accepted Manuscript.

ABSTRACT
Purpose :Epidemiologic studies in women have revealed an association between caffeine Intake and urinary incontinence (UI), though evidence among men is limited. The purpose of  this study was to evaluate the association between caffeine intake and UI among US men.

 

Materials and Methods: Data were used from male NHANES 2005 06 and 2007 08 participants. UI was defined using a standard questionnaire with Incontinence Severity Index  (ISI) scores > 3 categorized as moderate-severe. Structured dietary recall was used to determine caffeine consumption (mg/day),water intake (gm/day), and total dietary moisture  (gm/day). Stepwise multivariable logistic regression models were used to assess the association between caffeine intake at or above the 75^thand 90^th percentiles and having

moderate severe UI, controlling for potential confounders UI risk factors and prostate conditions in men >  40years.

Results: Among the  3,960 of5,297 (75%) aged>20 years with complete data, the prevalence of any UI was 12.9% and moderate severe UI was_4.4%. Mean caffeine intake was 169mg/day caffeine intake at the upper 75^th (>234 mg/day)and 90^th percentiles(>392_mg/day) were  significantly associated with having moderate severe UI;_(1.72, 95% 1.18-2.49) and (2.08 95% 1.15-3.77)respectively. After also adjusting for prostate conditions the effect size for the association between caffeine intake and moderate severe UI remained.