Forskning

February 26, 2013

The effect of acute café latter ingestion on fasting serum lipid levels in healthy individuals

A Zargar et al, 2013, The effect of acute café latter ingestion on fasting serum lipid levels in healthy individuals, Journal of Clinical Lipidology, published online ahead of print.

BACKGROUND: Many patients drink cafe latte as part of their habitual morning routine to start their day and may be unable to skip this step before drawing a fasting blood sample for cholesterol testing. However, it is unknown what the acute effects of consuming a cafe latte are on fasting serum lipids just before blood sampling.

OBJECTIVE: This was a prospective, open-label study with the primary objective of evaluating the acute effect of a 12-oz cafe latte (2% milk) on calculated low-density lipoprotein cholesterol (LDL-C) and secondary objectives of triglyceride, total cholesterol, high-density lipoprotein cholesterol (HDLC), non-HDL-C, and fasting blood glucose (FBG).

METHODS: A 10-hour fasting lipid profile was obtained before and 30 minutes after subjects consumed the cafe latte.

RESULTS: Forty-nine adult participants (34 females; age [mean 6 SD] 32.2 ± 13.2 years) were studied. No significant changes in total cholesterol, LDL-C, or non-HDL-C were observed after coffee consumption. Triglyceride significantly decreased from a median of 76.0 to 75.0 mg/dL (P = .002). HDL-C and FBG increased from a mean of 54.4 ± 12.7 to 56.4 ±14.5 mg/dL (P = .015) and 87.2 ± 7.0 to 97.3 ± 12.9 mg/dL (P , .001), respectively.

CONCLUSION: Consumption of 12 oz. of cafe latte within one hour of blood draw did not result in a significant change in LDL-C or non-HDL-C in young, non obese healthy individuals. However, FBG levels increased by almost 12%.