Forskning

April 30, 2014

Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women

S N Bhupathiraju et al, 2014, Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women, Diabetologia, published online ahead of print.

Human Study – Type 2 Diabetes

ABSTRACT: Aims/Hypothesis: Coffee and tea consumption has been associated with a lower type 2 diabetes risk but little is known about how changes in coffee and tea consumption influence subsequent type 2 diabetes risk. We examined the association between 4 year changes in coffee and tea consumption and risk of type 2 diabetes in the subsequent 4 years. Methods: We prospectively followed 48,464 women in the Nurses’ Health Study (NHS; 1986‐2006), 47,510 women in NHS II (1991‐2007) and 27,759 men in the Health Professionals Follow‐up Study (HPFS; 1986‐2006). Diet was assessed every 4 years using a validated food‐frequency questionnaire. Self‐reported cases of incident type 2 diabetes were validated by supplementary questionnaires. Results: During 1,663,319 person‐years of follow‐up, we documented 7,269 cases of incident type 2 diabetes. Participants who increased their coffee consumption by more than 1 cup/day (median change = 1.69 cups/day) over a 4 year period had an 11% (95% CI3%,18%) lower risk of type 2 diabetes in the subsequent 4 years compared with those who made no changes in consumption. Participants who decreased their coffee intake by more than 1 cup/day (median change =‐ 2cups/day) had a 17% (95% CI8%,26%) higher risk for type 2 diabetes. Changes in tea consumption were not associated with type 2 diabetes risk. Conclusions/interpretation: Our data provide novel evidence that increasing coffee consumption over a 4 year period is associated with a lower risk of type 2 diabetes, while decreasing coffee consumption is associated with a higher risk of type 2 diabetes in subsequent years.