April 30, 2014
N M Pham et al, 2014, Habitual consumption of coffee and green tea in relation to serum adipokines, European Journal of Nutrition, published online ahead of print.
Human Study – Adipokines
ABSTRACT: Purpose: Coffee and green tea consumption may be associated with circulating adipokines, but data are inconsistent, scarce or lacking. We examined the association of coffee and green tea consumption with serum adiponectin, leptin, visfatin, resisting and plasminogen activator inhibitor‐1 (PAI‐1) among a Japanese working population. Methods: The authors analyzed data (n = 509) from a cross‐sectional survey among Japanese workers aged 20–68 years. Serum adipokines were measured using a Luminex suspension bead based multiplexed array. Coffee and green tea consumption was assessed using a validated diet history questionnaire, and caffeine consumption from these beverages was estimated. Multiple regression analysis was performed with adjustment for potential confounding variables. Results: Coffee consumption was significantly, inversely associated with leptin and PAI‐1 (P for trend = 0.007 and 0.02, respectively); compared with subjects consuming <1 cup per day, those consuming ≥4 cups per day had 13 and 10 % lower means of leptin and PAI‐1, respectively. Similar associations were observed for caffeine consumption (P for trend = 0.02 for both leptin and PAI‐1). Additionally, we noted a significant positive association between coffee consumption and adiponectin in men (Pfor trend = 0.046), but not in women (P for trend = 0.43, P for interaction = 0.11). Moreover, there was a positive association between coffee consumption and resistin in current male smokers (P for trend = 0.01), but not in male non‐smokers (P for trend = 0.35, P for interaction = 0.11). Green tea consumption was not associated with any adipokine. Conclusions: Higher consumption of coffee and caffeine but not green tea was associated with lower serum levels of leptin and PAI‐1 in Japanese adults.
Ja tak, jeg vil gerne modtage nyhedsbrev, når der er noget nyt om kaffe og helbred.